Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q8N554
UPID:
ZN276_HUMAN
Alternative names:
Zinc finger protein 477
Alternative UPACC:
Q8N554; Q0VGA1; Q2TBE8; Q3B7H7
Background:
Zinc finger protein 276, also known as Zinc finger protein 477, plays a crucial role in transcriptional regulation. Its unique structure, characterized by the presence of zinc finger motifs, enables it to bind DNA and influence gene expression. This protein's involvement in transcriptional processes underscores its importance in cellular function and development.
Therapeutic significance:
Understanding the role of Zinc finger protein 276 could open doors to potential therapeutic strategies. Its pivotal function in gene regulation makes it a promising target for interventions aimed at modulating gene expression patterns in various diseases.