Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8WXA3
UPID:
RUFY2_HUMAN
Alternative names:
Rab4-interacting protein related
Alternative UPACC:
Q8WXA3; B3KXB2; B4DFR0; Q5TC48; Q8IW33; Q96P51; Q9P1Z1
Background:
The RUN and FYVE domain-containing protein 2, also known by its alternative name Rab4-interacting protein related, plays a crucial role in cellular processes. Its unique structure, characterized by the presence of RUN and FYVE domains, suggests a significant function in intracellular signaling and membrane trafficking.
Therapeutic significance:
Understanding the role of RUN and FYVE domain-containing protein 2 could open doors to potential therapeutic strategies.