Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q96FV2
UPID:
SCRN2_HUMAN
Alternative names:
-
Alternative UPACC:
Q96FV2; A8K3N1; B7Z8S7; E9PBV5; Q96AC3; Q9BU04
Background:
Secernin-2, encoded by the gene symbolized as Q96FV2, plays a pivotal role in cellular processes, although its specific functions remain to be fully elucidated. This protein's involvement in intracellular signaling pathways highlights its importance in maintaining cellular homeostasis and regulating cell function.
Therapeutic significance:
Understanding the role of Secernin-2 could open doors to potential therapeutic strategies. Its multifaceted role in biological systems makes it an intriguing subject for scientific inquiry, potentially leading to breakthroughs in treating diseases where cellular signaling and homeostasis are compromised.