Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q96QA6
UPID:
YPEL2_HUMAN
Alternative names:
-
Alternative UPACC:
Q96QA6; A0PK16; A2RUG4; Q65ZA0; Q8N3W2
Background:
Protein yippee-like 2, encoded by the gene symbol Q96QA6, plays a crucial role in cellular processes. Its unique structure and function position it as a key player in the regulation of cell growth and maintenance. The specific functions of Protein yippee-like 2, while not fully elucidated, are believed to be pivotal in maintaining cellular homeostasis.
Therapeutic significance:
Understanding the role of Protein yippee-like 2 could open doors to potential therapeutic strategies. Its involvement in fundamental cellular processes suggests that targeting this protein could lead to innovative treatments for diseases where cell regulation is compromised.