Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q9BXY5
UPID:
CAYP2_HUMAN
Alternative names:
Calcyphosine-2
Alternative UPACC:
Q9BXY5; Q6PH84; Q8N242; Q8NAY5
Background:
Calcyphosin-2, also known as Calcyphosine-2, is a protein encoded by the gene with the UniProt accession number Q9BXY5. While the specific functions of Calcyphosin-2 remain to be fully elucidated, its identification as a unique protein suggests a potential role in calcium signaling pathways, which are crucial for various cellular processes.
Therapeutic significance:
Understanding the role of Calcyphosin-2 could open doors to potential therapeutic strategies. Its involvement in calcium signaling pathways hints at its significance in cellular functions and disease mechanisms, making it a target of interest for drug discovery efforts.