Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9NXH8
UPID:
TOR4A_HUMAN
Alternative names:
Torsin family 4 member A
Alternative UPACC:
Q9NXH8; A2BFA4
Background:
Torsin-4A, also known as Torsin family 4 member A, plays a crucial role in cellular processes, although its specific functions remain to be fully elucidated. This protein's unique structure and alternative names highlight its potential significance in biological systems.
Therapeutic significance:
Understanding the role of Torsin-4A could open doors to potential therapeutic strategies. Its multifaceted role in biological systems makes it an intriguing subject for scientific inquiry, promising advancements in medical treatments.