Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q9P121
UPID:
NTRI_HUMAN
Alternative names:
IgLON family member 2
Alternative UPACC:
Q9P121; A0MTT2; Q6UXJ3; Q86VJ9
Background:
Neurotrimin, known as IgLON family member 2, is a neural cell adhesion molecule that plays a crucial role in the development and function of the nervous system. Its involvement in cell-cell interactions underpins its significance in neural network formation and synaptic plasticity.
Therapeutic significance:
Understanding the role of Neurotrimin could open doors to potential therapeutic strategies. Its pivotal function in neural development and synaptic connectivity positions it as a key target for interventions in neurological disorders.