Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q9UBL6
UPID:
CPNE7_HUMAN
Alternative names:
Copine VII
Alternative UPACC:
Q9UBL6
Background:
Copine-7, also known as Copine VII, is a calcium-dependent phospholipid-binding protein. It plays a crucial role in calcium-mediated intracellular processes, indicating its importance in cellular signaling and homeostasis.
Therapeutic significance:
Understanding the role of Copine-7 could open doors to potential therapeutic strategies. Its involvement in calcium-mediated processes suggests a foundational role in cellular function, which could be pivotal in disease treatment and prevention.