Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
A4FU69
UPID:
EFCB5_HUMAN
Alternative names:
-
Alternative UPACC:
A4FU69; B2RPN0; B4DS75; B4DZR5; F5GYL2; Q0VD68; Q6ZRM6; Q8NDG9
Background:
EF-hand calcium-binding domain-containing protein 5, identified by the accession number A4FU69, plays a crucial role in calcium signaling, a pivotal process in cellular communication and function. This protein, through its EF-hand calcium-binding domain, is involved in the regulation of various cellular processes, including muscle contraction, neurotransmitter release, and gene expression.
Therapeutic significance:
Understanding the role of EF-hand calcium-binding domain-containing protein 5 could open doors to potential therapeutic strategies. Its involvement in critical cellular processes underscores its potential as a target for drug discovery, aiming to modulate calcium signaling pathways for therapeutic benefits.