Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
This approach involves comprehensive molecular simulations of the catalytic and allosteric binding pockets and ensemble virtual screening that accounts for their conformational flexibility. In the case of designing modulators, the structural adjustments caused by reaction intermediates are considered to improve activity and selectivity.
Our library stands out due to several important features:
partner
Reaxense
upacc
A6NGE7
UPID:
URAD_HUMAN
Alternative names:
Parahox neighbor; Ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5-) decarboxylase
Alternative UPACC:
A6NGE7
Background:
The protein, known as Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase, and alternatively as Parahox neighbor and Ureidoimidazoline decarboxylase, plays a crucial role in the metabolic process. It catalyzes the stereoselective decarboxylation of 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin, showcasing its importance in biochemical pathways.
Therapeutic significance:
Understanding the role of Putative 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase could open doors to potential therapeutic strategies. Its unique enzymatic activity suggests a pivotal role in metabolic pathways, which could be leveraged in designing novel treatments.