Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
A6NGN9
UPID:
IGLO5_HUMAN
Alternative names:
-
Alternative UPACC:
A6NGN9
Background:
IgLON family member 5, encoded by the gene with accession number A6NGN9, is a protein of interest in the field of neurobiology. Its role, while not fully elucidated, is believed to be crucial in the development and functioning of the nervous system. The IgLON family is known for its involvement in cell adhesion processes, which are essential for neuronal growth and connectivity.
Therapeutic significance:
Understanding the role of IgLON family member 5 could open doors to potential therapeutic strategies. Its involvement in neural development and connectivity suggests that it could be a target for treating neurological disorders.