Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
B5MD39
UPID:
GGTL3_HUMAN
Alternative names:
Putative gamma-glutamyltransferase light chain 3
Alternative UPACC:
B5MD39; A6NEA2
Background:
Putative glutathione hydrolase light chain 3, also known as Putative gamma-glutamyltransferase light chain 3, plays a crucial role in cellular detoxification processes. This protein is involved in the cleavage of glutathione, a key molecule in the antioxidant defense system, facilitating the removal of harmful substances from the cell.
Therapeutic significance:
Understanding the role of Putative glutathione hydrolase light chain 3 could open doors to potential therapeutic strategies. Its involvement in detoxification processes makes it a promising target for the development of treatments aimed at enhancing cellular resilience to oxidative stress and toxins.