Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
O75131
UPID:
CPNE3_HUMAN
Alternative names:
Copine III
Alternative UPACC:
O75131; A8KA47; Q8IYA1
Background:
Copine-3, also known as Copine III, is a calcium-dependent phospholipid-binding protein. It plays a pivotal role in ERBB2-mediated tumor cell migration, responding to growth factor heregulin stimulation. This protein's involvement in cellular processes highlights its importance in biological systems.
Therapeutic significance:
Understanding the role of Copine-3 could open doors to potential therapeutic strategies. Its involvement in tumor cell migration underlines its potential as a target in cancer therapy, offering new avenues for treatment development.