Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
O95164
UPID:
UBL3_HUMAN
Alternative names:
Membrane-anchored ubiquitin-fold protein; Protein HCG-1
Alternative UPACC:
O95164; B2R4J1; Q5RL72; Q5VZS0; Q6FIG8; Q96SG7
Background:
Ubiquitin-like protein 3, also known as Membrane-anchored ubiquitin-fold protein and Protein HCG-1, plays a crucial role in cellular processes. Its unique structure, characterized by the ubiquitin-fold, suggests a significant function in protein degradation pathways, a fundamental process for maintaining cellular homeostasis.
Therapeutic significance:
Understanding the role of Ubiquitin-like protein 3 could open doors to potential therapeutic strategies. Its involvement in protein degradation pathways highlights its potential as a target for developing treatments aimed at diseases caused by protein accumulation or misfolding.