Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
O95755
UPID:
RAB36_HUMAN
Alternative names:
-
Alternative UPACC:
O95755; Q2M390; Q7Z4A9; Q9UHP5
Background:
Ras-related protein Rab-36 plays a crucial role in protein transport, facilitating vesicular traffic within cells. This process is essential for the proper functioning of cellular components, ensuring that proteins reach their designated locations. Rab-36, by its nature, is involved in the intricate network of vesicles, which are pivotal for transporting molecules across different parts of the cell.
Therapeutic significance:
Understanding the role of Ras-related protein Rab-36 could open doors to potential therapeutic strategies. Its involvement in protein transport and vesicular traffic highlights its importance in cellular function and health. Exploring Rab-36's mechanisms further could unveil new pathways for targeting diseases at the cellular level.