Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P01563
UPID:
IFNA2_HUMAN
Alternative names:
Interferon alpha-A
Alternative UPACC:
P01563; H2DF54; H2DF55; P01564; Q14606; Q6DJX8; Q96KI6
Background:
Interferon alpha-2, also known as Interferon alpha-A, is a pivotal protein produced by macrophages. It plays a crucial role in the body's defense mechanism against viral infections, showcasing significant antiviral activities. This protein is part of the interferon family, which are key players in the immune response against pathogens.
Therapeutic significance:
Understanding the role of Interferon alpha-2 could open doors to potential therapeutic strategies. Its antiviral properties make it a valuable target for research in developing treatments for viral infections. The exploration of Interferon alpha-2's functions and mechanisms offers promising avenues for novel antiviral therapies.