Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
P02042
UPID:
HBD_HUMAN
Alternative names:
Delta-globin; Hemoglobin delta chain
Alternative UPACC:
P02042; Q3Y5H3; Q8WXT7
Background:
Hemoglobin subunit delta, also known as Delta-globin or Hemoglobin delta chain, plays a crucial role in oxygen transport from the lungs to various peripheral tissues. This protein is a component of hemoglobin, the oxygen-carrying molecule in red blood cells, and is encoded by the P02042 gene.
Therapeutic significance:
Understanding the role of Hemoglobin subunit delta could open doors to potential therapeutic strategies. Its essential function in oxygen delivery highlights its potential impact on treating conditions related to oxygen deficiency.