Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
P05162
UPID:
LEG2_HUMAN
Alternative names:
Beta-galactoside-binding lectin L-14-II; HL14; Lactose-binding lectin 2; S-Lac lectin 2
Alternative UPACC:
P05162; Q6FGY4
Background:
Galectin-2, known for its ability to bind beta-galactoside, plays a crucial role in cellular processes, despite its physiological function being not fully understood. Also referred to as Beta-galactoside-binding lectin L-14-II, HL14, Lactose-binding lectin 2, and S-Lac lectin 2, this protein's intricate involvement in cellular mechanisms makes it a subject of significant scientific interest.
Therapeutic significance:
Understanding the role of Galectin-2 could open doors to potential therapeutic strategies. Its unique binding capabilities suggest a pivotal role in cellular communication and disease modulation, highlighting its importance in drug discovery and therapeutic development.