Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
P05386
UPID:
RLA1_HUMAN
Alternative names:
60S acidic ribosomal protein P1
Alternative UPACC:
P05386; A6NIB2
Background:
Large ribosomal subunit protein P1, also known as 60S acidic ribosomal protein P1, is crucial for protein synthesis. It plays a pivotal role in the elongation step, where amino acids are sequentially added to a growing polypeptide chain, facilitating the production of functional proteins.
Therapeutic significance:
Understanding the role of Large ribosomal subunit protein P1 could open doors to potential therapeutic strategies. Its essential function in protein synthesis makes it a potential target for developing treatments that require modulation of protein production.