Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
P07148
UPID:
FABPL_HUMAN
Alternative names:
Fatty acid-binding protein 1; Liver-type fatty acid-binding protein
Alternative UPACC:
P07148
Background:
The Fatty acid-binding protein, liver, also known as Liver-type fatty acid-binding protein and Fatty acid-binding protein 1, is pivotal in lipoprotein-mediated cholesterol uptake in hepatocytes. It has a unique ability to bind cholesterol and free fatty acids, along with their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm, suggesting a significant role in intracellular lipid transport.
Therapeutic significance:
Understanding the role of Fatty acid-binding protein, liver could open doors to potential therapeutic strategies.