Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We employ our advanced, specialised process to create targeted libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
It includes comprehensive molecular simulations of the catalytic and allosteric binding pockets and the ensemble virtual screening accounting for their conformational mobility. In the case of designing modulators, the structural changes induced by reaction intermediates are taken into account to leverage activity and selectivity.
Our library stands out due to several important features:
partner
Reaxense
upacc
P07864
UPID:
LDHC_HUMAN
Alternative names:
Cancer/testis antigen 32; LDH testis subunit; LDH-X
Alternative UPACC:
P07864; D3DQY4; Q6GSG8; Q7Z7J4
Background:
The L-lactate dehydrogenase C chain, known by alternative names such as Cancer/testis antigen 32, LDH testis subunit, and LDH-X, plays a crucial role in cellular processes. Its primary function is associated with a possible role in sperm motility, highlighting its importance in reproductive biology.
Therapeutic significance:
Understanding the role of L-lactate dehydrogenase C chain could open doors to potential therapeutic strategies. Its unique function in sperm motility makes it a target of interest for addressing reproductive health issues.