Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P08670
UPID:
VIME_HUMAN
Alternative names:
-
Alternative UPACC:
P08670; B0YJC2; D3DRU4; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3
Background:
Vimentin, encoded by the gene with accession number P08670, is a class-III intermediate filament predominantly found in mesenchymal cells. It plays a crucial role in maintaining cell integrity and is involved in various cellular processes, including cell division and differentiation. Vimentin's interaction with cellular structures such as the nucleus, endoplasmic reticulum, and mitochondria is essential for its function.
Therapeutic significance:
The association of Vimentin with 'Cataract 30, multiple types' highlights its potential impact on ocular health. Understanding the role of Vimentin could open doors to potential therapeutic strategies for treating or managing cataract conditions, emphasizing the importance of research in this area.