Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
P0CG37
UPID:
CFC1_HUMAN
Alternative names:
Cryptic family protein 1
Alternative UPACC:
P0CG37; B2RCY0; B9EJD3; Q53T05; Q9GZR3
Background:
Cryptic protein, also known as Cryptic family protein 1, plays a pivotal role in establishing the left-right axis, crucial for proper organ placement and symmetry in the body. It is involved in mesoderm and neural patterning during the early stages of embryonic development, indicating its fundamental role in gastrulation.
Therapeutic significance:
Given its association with Heterotaxy, visceral, 2, autosomal, a disorder characterized by abnormal organ placement and congenital defects, understanding the role of Cryptic protein could open doors to potential therapeutic strategies.