Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
P43364
UPID:
MAGAB_HUMAN
Alternative names:
Cancer/testis antigen 1.11; MAGE-11 antigen
Alternative UPACC:
P43364; Q5ETU4; Q6ZRZ5
Background:
Melanoma-associated antigen 11, also known as MAGE-11, is a protein that plays a crucial role in modulating androgen receptor activity, which is pivotal for embryonal development and may influence tumor transformation or progression. It is alternatively named Cancer/testis antigen 1.11 and MAGE-11 antigen.
Therapeutic significance:
Understanding the role of Melanoma-associated antigen 11 could open doors to potential therapeutic strategies, especially in the context of its involvement in modulating androgen receptor activity, a key player in various cancers.