Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We employ our advanced, specialised process to create targeted libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
The method includes detailed molecular simulations of the catalytic and allosteric binding pockets, along with ensemble virtual screening that considers their conformational flexibility. In the design of modulators, structural changes induced by reaction intermediates are taken into account to enhance activity and selectivity.
Key features that set our library apart include:
partner
Reaxense
upacc
P49903
UPID:
SPS1_HUMAN
Alternative names:
Selenium donor protein 1; Selenophosphate synthase 1
Alternative UPACC:
P49903; B4DWK0; D3DRS9; D6PSQ9; Q5T5U8; Q5T5U9; Q9BVT4
Background:
Selenide, water dikinase 1, also known as Selenium donor protein 1 and Selenophosphate synthase 1, plays a crucial role in synthesizing selenophosphate from selenide and ATP. This enzyme is pivotal in the incorporation of selenium into selenoproteins, which are essential for various cellular processes.
Therapeutic significance:
Understanding the role of Selenide, water dikinase 1 could open doors to potential therapeutic strategies. Its critical function in selenoprotein synthesis suggests its importance in maintaining cellular health and preventing disease.