Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P50120
UPID:
RET2_HUMAN
Alternative names:
Cellular retinol-binding protein II
Alternative UPACC:
P50120; A8K7G3; Q6ISQ9; Q6ISS7
Background:
Retinol-binding protein 2, also known as Cellular retinol-binding protein II, plays a crucial role in the intracellular transport of retinol. This protein is essential for the bioavailability and utilization of vitamin A, which is vital for vision, growth, and cellular differentiation.
Therapeutic significance:
Understanding the role of Retinol-binding protein 2 could open doors to potential therapeutic strategies. Its pivotal function in vitamin A metabolism highlights its importance in maintaining visual and systemic health.