Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We utilise our cutting-edge, exclusive workflow to develop focused libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
It includes in-depth molecular simulations of both the catalytic and allosteric binding pockets, with ensemble virtual screening focusing on their conformational flexibility. For modulators, the process includes considering the structural shifts due to reaction intermediates to boost activity and selectivity.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P53370
UPID:
NUDT6_HUMAN
Alternative names:
Antisense basic fibroblast growth factor; Protein GFG
Alternative UPACC:
P53370; A8K756; O95097; Q9UQD9
Background:
Nucleoside diphosphate-linked moiety X motif 6, also known as Antisense basic fibroblast growth factor or Protein GFG, is a protein encoded by the gene with the UniProt accession number P53370. It plays a crucial role in cellular processes, potentially contributing to the regulation of cell proliferation. This protein's involvement in fundamental cellular functions makes it a subject of significant interest in the field of molecular biology and biochemistry.
Therapeutic significance:
Understanding the role of Nucleoside diphosphate-linked moiety X motif 6 could open doors to potential therapeutic strategies. Its contribution to cell proliferation regulation suggests that further research could unveil novel approaches to targeting diseases characterized by abnormal cell growth.