Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
P59095
UPID:
STAR6_HUMAN
Alternative names:
START domain-containing protein 6
Alternative UPACC:
P59095
Background:
StAR-related lipid transfer protein 6, also known as START domain-containing protein 6, plays a crucial role in the intracellular transport of sterols and other lipids. Its ability to potentially bind cholesterol or other sterols highlights its significance in lipid metabolism processes.
Therapeutic significance:
Understanding the role of StAR-related lipid transfer protein 6 could open doors to potential therapeutic strategies. Its involvement in lipid transport and metabolism positions it as a key target for addressing disorders related to lipid imbalances.