Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We employ our advanced, specialised process to create targeted libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
The method includes detailed molecular simulations of the catalytic and allosteric binding pockets, along with ensemble virtual screening that considers their conformational flexibility. In the design of modulators, structural changes induced by reaction intermediates are taken into account to enhance activity and selectivity.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
P61020
UPID:
RAB5B_HUMAN
Alternative names:
-
Alternative UPACC:
P61020; A8K982; B4DKD7; P35239; P35277; Q6PIK9; Q86TH0; Q8IXL2
Background:
Ras-related protein Rab-5B plays a crucial role in protein transport, specifically in the regulation of vesicular traffic within cells. This protein is part of the larger Rab family, which is known for its importance in endocytosis and membrane trafficking.
Therapeutic significance:
Understanding the role of Ras-related protein Rab-5B could open doors to potential therapeutic strategies. Its pivotal function in cellular transport mechanisms positions it as a key target for research in disease intervention.