Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
P62249
UPID:
RS16_HUMAN
Alternative names:
40S ribosomal protein S16
Alternative UPACC:
P62249; B2RDD5; P17008
Background:
The Small ribosomal subunit protein uS9, also known as 40S ribosomal protein S16, plays a pivotal role in protein synthesis. As a component of the small ribosomal subunit, it is integral to the ribosome's function in translating mRNA into polypeptide chains. This process involves a complex orchestration of RNA folding, modifications, and cleavage, facilitated by the SSU processome in the nucleolus.
Therapeutic significance:
Understanding the role of Small ribosomal subunit protein uS9 could open doors to potential therapeutic strategies. Its critical function in protein synthesis makes it a potential target for interventions in diseases where protein production is dysregulated.