Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We utilise our cutting-edge, exclusive workflow to develop focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
P62888
UPID:
RL30_HUMAN
Alternative names:
60S ribosomal protein L30
Alternative UPACC:
P62888; B2R591; P04645; Q502Z6
Background:
The Large ribosomal subunit protein eL30, also known as 60S ribosomal protein L30, plays a crucial role in the ribosome, the cell's protein synthesis machinery. It is a component of the large ribosomal subunit, essential for the accurate and efficient translation of mRNA into proteins.
Therapeutic significance:
Understanding the role of Large ribosomal subunit protein eL30 could open doors to potential therapeutic strategies. Its pivotal function in protein synthesis makes it a potential target for developing treatments that require modulation of protein production.