Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
P82980
UPID:
RET5_HUMAN
Alternative names:
Cellular retinol-binding protein III; HRBPiso
Alternative UPACC:
P82980; Q53FB1
Background:
Retinol-binding protein 5, also known as Cellular retinol-binding protein III or HRBPiso, plays a crucial role in the intracellular transport of retinol. This protein is pivotal for the mobilization and storage of retinol within cells, facilitating its availability for critical biological processes.
Therapeutic significance:
Understanding the role of Retinol-binding protein 5 could open doors to potential therapeutic strategies. Its involvement in the transport of retinol highlights its importance in maintaining cellular health and function, suggesting avenues for intervention in conditions where retinol metabolism is disrupted.