Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Several key aspects differentiate our library:
partner
Reaxense
upacc
Q02045
UPID:
MYL5_HUMAN
Alternative names:
Myosin regulatory light chain 5; Superfast myosin regulatory light chain 2
Alternative UPACC:
Q02045; Q8IXL8
Background:
Myosin light chain 5, also known as Myosin regulatory light chain 5 and Superfast myosin regulatory light chain 2, plays a crucial role in muscle contraction mechanics. It is a component of the myosin complex, essential for the cyclic interaction between actin and myosin, driving muscle contractions.
Therapeutic significance:
Understanding the role of Myosin light chain 5 could open doors to potential therapeutic strategies. Its pivotal function in muscle contraction highlights its potential as a target for treating muscle-related disorders.