Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q08ET2
UPID:
SIG14_HUMAN
Alternative names:
-
Alternative UPACC:
Q08ET2; Q6UXG0
Background:
Sialic acid-binding Ig-like lectin 14, a putative adhesion molecule, plays a crucial role in cellular communication and immune response through its ability to bind sialic acid. This protein's unique sialic acid-binding capacity suggests a significant function in modulating cell-cell interactions.
Therapeutic significance:
Understanding the role of Sialic acid-binding Ig-like lectin 14 could open doors to potential therapeutic strategies. Its involvement in cellular adhesion and immune response positions it as a key target for drug discovery efforts aimed at treating a wide range of diseases.