Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q0VAA5
UPID:
PLCX2_HUMAN
Alternative names:
-
Alternative UPACC:
Q0VAA5; Q96N12
Background:
PI-PLC X domain-containing protein 2 plays a crucial role in cellular processes, leveraging its unique domain structure to participate in intricate signaling pathways. This protein, encoded by the gene symbolized as Q0VAA5, is pivotal in the modulation of intracellular environments, impacting cell proliferation, differentiation, and survival.
Therapeutic significance:
Understanding the role of PI-PLC X domain-containing protein 2 could open doors to potential therapeutic strategies. Its involvement in key cellular functions suggests that targeted interventions in its signaling pathways may offer novel approaches for disease management and treatment.