Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q15814
UPID:
TBCC_HUMAN
Alternative names:
Tubulin-folding cofactor C
Alternative UPACC:
Q15814; Q53Y43; Q5T787
Background:
Tubulin-specific chaperone C, also known as Tubulin-folding cofactor C, plays a crucial role in the tubulin folding pathway, a final step essential for the proper assembly of microtubules. This protein ensures the correct folding of tubulin, a structural component vital for cell division and intracellular transport.
Therapeutic significance:
Understanding the role of Tubulin-specific chaperone C could open doors to potential therapeutic strategies. Its pivotal function in microtubule assembly highlights its importance in cellular processes, suggesting that modulation of its activity could influence cell division and potentially target diseases characterized by abnormal cell proliferation.