Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library stands out due to several important features:
partner
Reaxense
upacc
Q32M78
UPID:
ZN699_HUMAN
Alternative names:
Hangover homolog
Alternative UPACC:
Q32M78; Q8N9A1
Background:
Zinc finger protein 699, also known as Hangover homolog, plays a crucial role in transcriptional regulation. Its unique structure, characterized by zinc finger motifs, suggests a significant function in gene expression modulation. This protein's involvement in critical biological processes underscores its importance in cellular mechanisms.
Therapeutic significance:
Linked to DEGCAGS syndrome, a complex neurodevelopmental disorder, Zinc finger protein 699's study offers insights into its pathogenic mechanisms. Understanding the role of Zinc finger protein 699 could open doors to potential therapeutic strategies, highlighting its importance in medical research and drug discovery.