Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q49AG3
UPID:
ZBED5_HUMAN
Alternative names:
Transposon-derived Buster1 transposase-like protein
Alternative UPACC:
Q49AG3; B2RCC1; Q05D82; Q86WW3; Q9NT24; Q9UBJ4
Background:
Zinc finger BED domain-containing protein 5, also known as Transposon-derived Buster1 transposase-like protein, plays a crucial role in the regulation of gene expression and DNA binding. Its unique zinc finger BED domain suggests a specific function in chromatin organization and transcriptional regulation, contributing to cellular homeostasis and development.
Therapeutic significance:
Understanding the role of Zinc finger BED domain-containing protein 5 could open doors to potential therapeutic strategies. Its involvement in gene expression regulation highlights its potential as a target for modulating disease-related genes, offering new avenues for drug discovery.