Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Utilising molecular simulations, our approach thoroughly examines a wide array of proteins, tracking their conformational changes individually and within complexes. Ensemble virtual screening enables us to address conformational flexibility, revealing essential binding sites at functional regions and allosteric locations. Our rigorous analysis guarantees that no potential mechanism of action is overlooked, aiming to uncover new therapeutic targets and lead compounds across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q5H913
UPID:
AR13A_HUMAN
Alternative names:
-
Alternative UPACC:
Q5H913; B2RTT6; B4DX50
Background:
ADP-ribosylation factor-like protein 13A plays a crucial role in cellular processes, including intracellular trafficking and actin cytoskeleton remodeling. Its involvement in these processes highlights its importance in maintaining cellular integrity and function.
Therapeutic significance:
Understanding the role of ADP-ribosylation factor-like protein 13A could open doors to potential therapeutic strategies. Its pivotal role in cellular mechanisms makes it a promising target for drug discovery, aiming to modulate its activity for therapeutic benefits.