Explore the Potential with AI-Driven Innovation
The specialised, focused library is developed on demand with the most recent virtual screening and parameter assessment technology, guided by the Receptor.AI drug discovery platform. This approach exceeds the capabilities of traditional methods and offers compounds with higher activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q5JSS6
UPID:
MEIG1_HUMAN
Alternative names:
-
Alternative UPACC:
Q5JSS6
Background:
The Meiosis expressed gene 1 protein homolog, identified by the accession number Q5JSS6, plays a pivotal role in the process of spermiogenesis. This protein is essential for the proper development of sperm, highlighting its significance in reproductive biology.
Therapeutic significance:
Understanding the role of Meiosis expressed gene 1 protein homolog could open doors to potential therapeutic strategies. Its critical function in spermiogenesis suggests that further research could lead to advancements in treatments for male infertility.