Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
From a virtual chemical space containing more than 60 billion molecules, we precisely choose certain compounds. Our collaborator, Reaxense, aids in their synthesis and provision.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q5T2N8
UPID:
ATD3C_HUMAN
Alternative names:
-
Alternative UPACC:
Q5T2N8; Q8N1Z5
Background:
ATPase family AAA domain-containing protein 3C plays a crucial role in cellular processes by utilizing the energy from ATP hydrolysis to remodel or translocate a wide variety of substrates. This protein, encoded by the gene with the UniProt accession number Q5T2N8, is part of the AAA (ATPases Associated with diverse cellular Activities) family, known for their significance in protein homeostasis, membrane trafficking, and organelle biogenesis.
Therapeutic significance:
Understanding the role of ATPase family AAA domain-containing protein 3C could open doors to potential therapeutic strategies. Its involvement in fundamental cellular processes makes it a promising target for drug discovery, aiming to modulate its activity in disease contexts.