Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q5VT79
UPID:
AXA81_HUMAN
Alternative names:
-
Alternative UPACC:
Q5VT79; A0A0B4J2D4; B2R939; Q53FY2; Q5VT78; Q96H89
Background:
Annexin A8-like protein 1, encoded by the gene with accession number Q5VT79, belongs to the annexin family of proteins known for their role in cellular processes such as membrane trafficking and signal transduction. Despite its similarity to other annexins, the specific functions of Annexin A8-like protein 1 remain to be fully elucidated.
Therapeutic significance:
Understanding the role of Annexin A8-like protein 1 could open doors to potential therapeutic strategies. Its unique structure and potential functions make it an intriguing subject for scientific inquiry, with the possibility of contributing to novel treatments for diseases.