Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library includes a list of the most promising modulators annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Also, each compound is presented with its optimal docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q6ZSU1
UPID:
C2G1P_HUMAN
Alternative names:
Cytochrome P450 2G1 pseudogene
Alternative UPACC:
Q6ZSU1
Background:
The Putative inactive cytochrome P450 2G1, also known as Cytochrome P450 2G1 pseudogene, represents a unique facet of the cytochrome P450 family, which is pivotal in the metabolism of various substances. Despite its designation as a pseudogene, its presence underscores the complexity and evolutionary dynamics within the cytochrome P450 superfamily.
Therapeutic significance:
Understanding the role of Putative inactive cytochrome P450 2G1 could open doors to potential therapeutic strategies. Its connection to the cytochrome P450 family, a critical component in drug metabolism, suggests that further exploration could yield insights into novel drug interactions and metabolic pathways.