Explore the Potential with AI-Driven Innovation
Our detailed focused library is generated on demand with advanced virtual screening and parameter assessment technology powered by the Receptor.AI drug discovery platform. This method surpasses traditional approaches, delivering compounds of better quality with enhanced activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
We use our state-of-the-art dedicated workflow for designing focused libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Our library distinguishes itself through several key aspects:
partner
Reaxense
upacc
Q70IA8
UPID:
MOB3C_HUMAN
Alternative names:
Mob1 homolog 2C; Mps one binder kinase activator-like 2C
Alternative UPACC:
Q70IA8; D3DQ22; Q0VA98; Q5TC10; Q5TC11; Q8NAZ2; Q8NF28
Background:
MOB kinase activator 3C, also known as Mob1 homolog 2C or Mps one binder kinase activator-like 2C, plays a crucial role in cellular processes by potentially regulating the activity of kinases. This protein, identified by the accession number Q70IA8, is a pivotal component in the signaling pathways that govern cell proliferation, differentiation, and survival.
Therapeutic significance:
Understanding the role of MOB kinase activator 3C could open doors to potential therapeutic strategies. Its involvement in kinase regulation suggests a significant impact on cellular functions, making it a promising target for drug discovery efforts aimed at treating diseases with dysregulated cell signaling.