Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
The library features a range of promising modulators, each detailed with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Plus, each compound is presented with its ideal docking poses, affinity scores, and activity scores, ensuring a thorough insight.
We use our state-of-the-art dedicated workflow for designing focused libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
The method includes detailed molecular simulations of the catalytic and allosteric binding pockets, along with ensemble virtual screening that considers their conformational flexibility. In the design of modulators, structural changes induced by reaction intermediates are taken into account to enhance activity and selectivity.
Key features that set our library apart include:
partner
Reaxense
upacc
Q7Z5A4
UPID:
PRS42_HUMAN
Alternative names:
Serine protease 42, pseudogene; Testis serine protease 2
Alternative UPACC:
Q7Z5A4
Background:
The Putative serine protease 42, also known as Testis serine protease 2, plays a crucial role in spermatogenesis. It is specifically involved in germ cell survival during meiosis, highlighting its importance in reproductive biology. Alternative names for this protein include Serine protease 42, pseudogene.
Therapeutic significance:
Understanding the role of Putative serine protease 42 could open doors to potential therapeutic strategies. Its pivotal function in germ cell survival suggests that further exploration could yield significant insights into reproductive health and disease.