Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
We carefully select specific compounds from a vast collection of over 60 billion molecules in virtual chemical space. Our partner Reaxense helps in synthesizing and delivering these compounds.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
We use our state-of-the-art dedicated workflow for designing focused libraries for enzymes.
Fig. 1. The sreening workflow of Receptor.AI
This approach involves comprehensive molecular simulations of the catalytic and allosteric binding pockets and ensemble virtual screening that accounts for their conformational flexibility. In the case of designing modulators, the structural adjustments caused by reaction intermediates are considered to improve activity and selectivity.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q86SG7
UPID:
LYG2_HUMAN
Alternative names:
-
Alternative UPACC:
Q86SG7; Q496G2; Q53RW0
Background:
Lysozyme g-like protein 2, encoded by the gene with accession number Q86SG7, is identified as a potent antibacterial protein. Its primary function is to play a crucial role in the innate immune system, defending the body against bacterial pathogens by disrupting their cell walls.
Therapeutic significance:
Understanding the role of Lysozyme g-like protein 2 could open doors to potential therapeutic strategies. Its antibacterial properties make it a promising target for developing new antimicrobial agents, especially in an era where antibiotic resistance is a growing concern.