Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
We pick out particular compounds from an extensive virtual database of more than 60 billion molecules. The preparation and shipment of these compounds are facilitated by our associate Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
Our top-notch dedicated system is used to design specialised libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology employs molecular simulations to explore a wide array of proteins, capturing their dynamic states both individually and within complexes. Through ensemble virtual screening, we address conformational mobility, uncovering binding sites within functional regions and remote allosteric locations. This thorough exploration ensures no potential mechanism of action is overlooked, aiming to discover novel therapeutic targets and lead compounds across an extensive spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q86VD1
UPID:
MORC1_HUMAN
Alternative names:
Cancer/testis antigen 33
Alternative UPACC:
Q86VD1; B4DYX1; E7ERX1; Q7L8E2; Q9NSG7; Q9Y6D4
Background:
MORC family CW-type zinc finger protein 1, also known as Cancer/testis antigen 33, plays a pivotal role in spermatogenesis, akin to its function in other species. It is crucial for the establishment of de novo DNA methylation patterns and the silencing of transposable elements in male embryonic germ cells, ensuring genomic stability and proper development.
Therapeutic significance:
Understanding the role of MORC family CW-type zinc finger protein 1 could open doors to potential therapeutic strategies. Its essential function in germ cell development highlights its potential as a target for addressing infertility issues and the regulation of transposable elements, which could have implications for cancer and other diseases where genomic stability is compromised.