Explore the Potential with AI-Driven Innovation
This comprehensive focused library is produced on demand with state-of-the-art virtual screening and parameter assessment technology driven by Receptor.AI drug discovery platform. This approach outperforms traditional methods and provides higher-quality compounds with superior activity, selectivity and safety.
The compounds are cherry-picked from the vast virtual chemical space of over 60B molecules. The synthesis and delivery of compounds is facilitated by our partner Reaxense.
Contained in the library are leading modulators, each labelled with 38 ADME-Tox and 32 physicochemical and drug-likeness qualities. In addition, each compound is illustrated with its optimal docking poses, affinity scores, and activity scores, giving a complete picture.
We employ our advanced, specialised process to create targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
By deploying molecular simulations, our approach comprehensively covers a broad array of proteins, tracking their flexibility and dynamics individually and within complexes. Ensemble virtual screening is utilised to take into account conformational dynamics, identifying pivotal binding sites located within functional regions and at allosteric locations. This thorough exploration ensures that every conceivable mechanism of action is considered, aiming to identify new therapeutic targets and advance lead compounds throughout a vast spectrum of biological functions.
Our library is unique due to several crucial aspects:
partner
Reaxense
upacc
Q86YA3
UPID:
ZGRF1_HUMAN
Alternative names:
GRF-type zinc finger domain-containing protein 1
Alternative UPACC:
Q86YA3; B3KQX2; B4DSN6; B4DYU8; E9PDE1; G5EA02; Q6ZU11; Q9NSW3; Q9NUJ4
Background:
Protein ZGRF1, also known as GRF-type zinc finger domain-containing protein 1, plays a crucial role in cellular processes through its involvement in the regulation of gene expression. The presence of a GRF-type zinc finger domain suggests its potential interaction with DNA or RNA, implicating it in complex regulatory networks within the cell.
Therapeutic significance:
Understanding the role of Protein ZGRF1 could open doors to potential therapeutic strategies. Its involvement in the regulation of gene expression makes it a promising target for the development of novel treatments aimed at modulating gene activity in disease states.