Explore the Potential with AI-Driven Innovation
The focused library is created on demand with the latest virtual screening and parameter assessment technology, supported by the Receptor.AI drug discovery platform. This method is more effective than traditional methods and results in higher-quality compounds with better activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
The library includes a list of the most effective modulators, each annotated with 38 ADME-Tox and 32 physicochemical and drug-likeness parameters. Furthermore, each compound is shown with its optimal docking poses, affinity scores, and activity scores, offering a detailed summary.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our strategy employs molecular simulations to explore an extensive range of proteins, capturing their dynamics both individually and within complexes with other proteins. Through ensemble virtual screening, we address proteins' conformational mobility, uncovering key binding sites at both functional regions and remote allosteric locations. This comprehensive investigation ensures a thorough assessment of all potential mechanisms of action, with the goal of discovering innovative therapeutic targets and lead molecules across across diverse biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8IWZ5
UPID:
TRI42_HUMAN
Alternative names:
-
Alternative UPACC:
Q8IWZ5; A1L4B4; A1L4B6; Q8N832; Q8NDL3
Background:
Tripartite motif-containing protein 42 plays a crucial role in cellular processes, although its specific functions are yet to be fully elucidated. This protein, encoded by the gene symbol Q8IWZ5, is part of a larger family known for their involvement in various cellular mechanisms, including intracellular signaling pathways and immune responses.
Therapeutic significance:
Understanding the role of Tripartite motif-containing protein 42 could open doors to potential therapeutic strategies. Its involvement in key cellular processes suggests that it could be a target for drug discovery, aiming to modulate its activity for therapeutic benefits.