Explore the Potential with AI-Driven Innovation
This extensive focused library is tailor-made using the latest virtual screening and parameter assessment technology, operated by the Receptor.AI drug discovery platform. This technique is more effective than traditional methods, offering compounds with improved activity, selectivity, and safety.
Our selection of compounds is from a large virtual library of over 60 billion molecules. The production and distribution of these compounds are managed by our partner Reaxense.
In the library, a selection of top modulators is provided, each marked with 38 ADME-Tox and 32 parameters related to physicochemical properties and drug-likeness. Also, every compound comes with its best docking poses, affinity scores, and activity scores, providing a comprehensive overview.
Our high-tech, dedicated method is applied to construct targeted libraries.
Fig. 1. The sreening workflow of Receptor.AI
Our methodology leverages molecular simulations to examine a vast array of proteins, capturing their dynamics in both isolated forms and in complexes with other proteins. Through ensemble virtual screening, we thoroughly account for the protein's conformational mobility, identifying critical binding sites within functional regions and distant allosteric locations. This detailed exploration ensures that we comprehensively assess every possible mechanism of action, with the objective of identifying novel therapeutic targets and lead compounds that span a wide spectrum of biological functions.
Key features that set our library apart include:
partner
Reaxense
upacc
Q8IX05
UPID:
CD302_HUMAN
Alternative names:
C-type lectin BIMLEC; C-type lectin domain family 13 member A; DEC205-associated C-type lectin 1; Type I transmembrane C-type lectin receptor DCL-1
Alternative UPACC:
Q8IX05; A8K5G4; B4E2T9; Q15009
Background:
CD302 antigen, also known as C-type lectin BIMLEC, plays a pivotal role in various biological processes including endocytosis, phagocytosis, cell adhesion, and migration. This multifunctional C-type lectin receptor, identified by the accession number Q8IX05, is a type I transmembrane protein that may serve as a key player in immune response modulation.
Therapeutic significance:
Understanding the role of CD302 antigen could open doors to potential therapeutic strategies. Its involvement in critical cellular functions suggests that targeting CD302 could offer novel approaches in treating diseases where these processes are dysregulated.